Sermorelin feedback

[hardasnails1973]

Dr john I was wondering if you have been getting postiive feedback from Sermorelin. I have been doing some research on it and it looks very promising. It appears to be the equliavemnt to hcg for your nutts in response to stimulating gh out from the pituirary. If a person was taking 1 ius of hgh for HRT would that equal approximately 333 mcgs of Sermorelin. Thanks for your imput. My Dr is very curious since I have been mentioning to him as a safer alternative to gh since it does not shrink the pituirary rather then actually regenreates the dorminat gh cells

[Dr. John Crisler]

The pituaitary has shown to rapidly recover somatotrophic acitvity.

We are just now getting into the initial rounds of follow-up testing s/p (status post) initiation of GHRT employing Sermorelin. I don't believe one month is long enough assess it's final stimulation.

Many of the guys say they are sleeping much better on it.

I'll continue to share what we learn as we go along.

[Wise Guy]

Good stuff, Im curious as well(low IGF-1)

If I recall its quite pricey at 6 bucks a day right

[hardasnails1973]

let calcuat $225 = 6mg = 18 ius of GH = 18 days = 400 mcg of sem a day = 225 x2 = 450 a month /30 more like 15 bucks a day bro LOL
I suck at english but I do agree my math is alot better (if my conversions are correct) HAHA

[Wise Guy]

let calcuat $225 = 6mg = 18 ius of GH = 18 days = 400 mcg of sem a day = 225 x2 = 450 a month /30 more like 15 bucks a day bro LOL
I suck at english but I do agree my math is alot better (if my conversions are correct) HAHA

Your math is much better :D

If i recall I think most though are using 200mcg per day not 400.

It might be weight dependent. Good for me if it is

At 200mcg, that would make it $7.50

Its actually doable. I use to spend way more than that a day on cigarettes, coffee and beer.

Lets wait and see how it pans out. A couple guys on another board reported some not so good outcomes from it. But a friend on it is raving about it. So who knows :confused:

[BigJimcalhoun]

Its actually doable. I use to spend way more than that a day on cigarettes, coffee and beer.
:

But for those of us stocking up on the third element of what the Bureau of ATF controls, we are saving/spending every dime we have.:D

[Wise Guy]

But for those of us stocking up on the third element of what the Bureau of ATF controls, we are saving/spending every dime we have.:D

I've got a couple of those as well :D

[Dr. John Crisler]

Your math is much better :D

If i recall I think most though are using 200mcg per day not 400.

It might be weight dependent. Good for me if it is

At 200mcg, that would make it $7.50

Its actually doable. I use to spend way more than that a day on cigarettes, coffee and beer.

Lets wait and see how it pans out. A couple guys on another board reported some not so good outcomes from it. But a friend on it is raving about it. So who knows :confused:

I've learned it takes about six weeks for it to begin to work, as evidenced by IGF-1 levels. It also depends upon whether the system was immediately suppressed by GH.

It's anecdotal, but many are saying they began sleeping better right off the bat, and losing weight as well.

Sorry, this is the way it is at the cutting edge.

[Wise Guy]

Any updates from Dr John or any one else?

[smitty4]

Don't mean to beat a dead thread, but I sure would love to hear if anyone has any additional information to report. I have been very intersted in Sermorelin, but I have also been wondering if many of the men on Test might have pituitary issues. If so, Sermorelin may not be ideal for them.

I am on Test, Armour, and have used HGH in the past (all prescribed by they way). That combination tends to make me wonder if my pituitary is worth a darn to begin with.

[Diancecht]

I saw Dr. Crisler on Friday. I will be starting the sermorelin soon as it should be here any day now.

[smitty4]

The pituaitary has shown to rapidly recover somatotrophic acitvity.

We are just now getting into the initial rounds of follow-up testing s/p (status post) initiation of GHRT employing Sermorelin. I don't believe one month is long enough assess it's final stimulation.

Many of the guys say they are sleeping much better on it.

I'll continue to share what we learn as we go along.

I remain interested in Sermorelin. Any updates Dr. John?

[Wise Guy]

The pituaitary has shown to rapidly recover somatotrophic acitvity.



Are you saying that the people on GH are showing an ability to bounce back and go natural w/ sermorelin:confused:

Or are people with low IGF-1 levels are showing great results and IGF-1 scores are shooting up on sermorelin :confused:

Or maybe both :cool:

[hardasnails1973]

Are you saying that the people on GH are showing an ability to bounce back and go natural w/ sermorelin:confused:

Or are people with low IGF-1 levels are showing great results and IGF-1 scores are shooting up on sermorelin :confused:

Or maybe both :cool:

its only a matter of time untill you see this HRT drug get used for other purpose. (i think you know where I am going with this)

[Diancecht]

Fortunately, taking massive doses of sermorelin is unlikely to push the IGF levels past the top normal range (in theory anyway). As such those who want go way past the levels needed for health may very well find it way to expensive for the gains desired. Hopefully therefore it wont become a drug of abuse.

I am not 100% sure here but I think that prior use of HGH may cause it to take longer to work. One of the theoretical issues with using HGH is that it could cause a downregulation of receptors etc and it gland will have to recover. On the other hand one of theories of use of sermorelin is that not only will it cause natural HGH secretion but also improve the function of the gland so it will secrete more HGH even when the sermorelin is no longer in the system thus prolonging and maintain gland function. Dr Crisler knows much more about it than me and I am sure will keep us updated.

Personally I started the sermorelin a little over two weeks ago. I did notice I was sleeping bette but the skeptical part of me wanted to write it off as placebo effect. However two days ago I awoke in the morning noticing I hadnt slept as well as normal and then I remembered I had forgotten the dose the evening before. I dont know if that means it is working and its way to expensive for use as a sleep aid. However HGH is normally secreted most during hours of sleep and perhaps we are seeing sleep effect from the increased amounts of HGH that are being stimulated to release into the system.

[Headdoc]

I started compounded GH in 6/04. My baseline was 80 ng/mL for IGF-1. For the next 3+ years the levels for IGF-1 hung around 250-325. Most assays were below 300. In September of 2007 I started sermorelin at 200 mcg. Two months later, the IGF-1 was 130. Since I'm a big guy: 6'1", 245, I read Richard Walker's material again and decided that I could benefit from a higher dose. I took it up to 400 mcg for 2 months. The IGF-1 lab came back at 126 ng/mL. Clinically, I may have gotten a mild sleep assist. Otherwize, nadda! So I'm hoping that at some point compounded GH comes back (after the Olympics?). The cost of running 400 mcg puts it in the same bracket as manufactured GH and it's just beyond my means right now. I got no weight loss effect from the sermorelin. I will admit that I was on GH for a long time uninterrupted and maybe 6-7 months is not enough of a trial for the sermorelin. IGFBP-3 has remained around 4000 for the past 4 years.

[Headdoc]

Fortunately, taking massive doses of sermorelin is unlikely to push the IGF levels past the top normal range (in theory anyway). As such those who want go way past the levels needed for health may very well find it way to expensive for the gains desired. Hopefully therefore it wont become a drug of abuse.

I am not 100% sure here but I think that prior use of HGH may cause it to take longer to work. One of the theoretical issues with using HGH is that it could cause a downregulation of receptors etc and it gland will have to recover. On the other hand one of theories of use of sermorelin is that not only will it cause natural HGH secretion but also improve the function of the gland so it will secrete more HGH even when the sermorelin is no longer in the system thus prolonging and maintain gland function. Dr Crisler knows much more about it than me and I am sure will keep us updated.

Personally I started the sermorelin a little over two weeks ago. I did notice I was sleeping bette but the skeptical part of me wanted to write it off as placebo effect. However two days ago I awoke in the morning noticing I hadnt slept as well as normal and then I remembered I had forgotten the dose the evening before. I dont know if that means it is working and its way to expensive for use as a sleep aid. However HGH is normally secreted most during hours of sleep and perhaps we are seeing sleep effect from the increased amounts of HGH that are being stimulated to release into the system.

.......on the other hand, maybe for a 63 year old guy, 130 may be all that a functioning pituitary would produce. Hence without having re-established a post GH baseline, I cannot say that sermorelin didn't help. So what do I get from 130 IGF-1? If I continue to exercise, eat right, sleep well, and take my testosterone, I get some GH. Think that I will get an IGF-1 once I'm off for 6-8 weeks.

[Diancecht]

I am wondering if anyone knows the reasoning for injecting the sermorelin at bedtime. Is it perhaps to be in tune with the natural secretory cycle HGH secretion in the hours of sleep.

If that is true would it be just as reasonable to inject it as alternative to the HS just before doing heavy wt training. For example Saturday is my heavy work out day. I start at 10 AM with a 1 hr private lesson in brazilian jiu-jitsu, I then do about a half hour of kettlebells, from 11 to 12. Then the regular brazlian jiu-jitsu class from 12 to 1:30. After a good shower (ew.. I really need one by then) I go for a nice 1.5 hr massage. The rationale is that heavy wt training and strength training also stimulates HGH secretion and so would I get a better response by doing.

On the other hand sermorelin is so new that its probably smartest to decrease the variables as much as possible to determine its relative value and effectiveness.

[Dr. John Crisler]

let calcuat $225 = 6mg = 18 ius of GH = 18 days = 400 mcg of sem a day = 225 x2 = 450 a month /30 more like 15 bucks a day bro LOL
I suck at english but I do agree my math is alot better (if my conversions are correct) HAHA
We're dispensing it at entirely comparable price.

And we dispensed GH at prices much less than anyone else to start.

[Dr. John Crisler]

Are you saying that the people on GH are showing an ability to bounce back and go natural w/ sermorelin:confused:

Or are people with low IGF-1 levels are showing great results and IGF-1 scores are shooting up on sermorelin :confused:

Or maybe both :cool:
The idea is to restore GH production while on Sermorelin.

[Dr. John Crisler]

Fortunately, taking massive doses of sermorelin is unlikely to push the IGF levels past the top normal range (in theory anyway). As such those who want go way past the levels needed for health may very well find it way to expensive for the gains desired. Hopefully therefore it wont become a drug of abuse.

I am not 100% sure here but I think that prior use of HGH may cause it to take longer to work. One of the theoretical issues with using HGH is that it could cause a downregulation of receptors etc and it gland will have to recover. On the other hand one of theories of use of sermorelin is that not only will it cause natural HGH secretion but also improve the function of the gland so it will secrete more HGH even when the sermorelin is no longer in the system thus prolonging and maintain gland function. Dr Crisler knows much more about it than me and I am sure will keep us updated.

Personally I started the sermorelin a little over two weeks ago. I did notice I was sleeping bette but the skeptical part of me wanted to write it off as placebo effect. However two days ago I awoke in the morning noticing I hadnt slept as well as normal and then I remembered I had forgotten the dose the evening before. I dont know if that means it is working and its way to expensive for use as a sleep aid. However HGH is normally secreted most during hours of sleep and perhaps we are seeing sleep effect from the increased amounts of HGH that are being stimulated to release into the system.
Reports are anecdotal--and consistent.