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medgerton
01-28-2009, 10:42 PM
I received a new vile of Novarel today. For some crazy reason I decided to read the drug information insert. Under the dosage section for selected cases of hypogonadotropic hypogonadism in males:

1. 500 to 1000 USP units 3 times per week for three weeks. Followed by the same dose for twice a week for three weeks

2. 4000 USP units three times weekly for 6 to 9 months. Followed by a reduction to 2000 USP units 3 times weekly for an additional three months.


I am assuming that USP unit equals IU.

Seems odd that a drug manufacturer would recommend a dose that would damage Leydig cells per Dr. John's HCG statement that a dose greater than 500 IU at one time causes Leydig cell desensitivity.

JanSz
01-29-2009, 12:53 PM
I received a new vile of Novarel today. For some crazy reason I decided to read the drug information insert. Under the dosage section for selected cases of hypogonadotropic hypogonadism in males:

1. 500 to 1000 USP units 3 times per week for three weeks. Followed by the same dose for twice a week for three weeks

2. 4000 USP units three times weekly for 6 to 9 months. Followed by a reduction to 2000 USP units 3 times weekly for an additional three months.


I am assuming that USP unit equals IU.

Seems odd that a drug manufacturer would recommend a dose that would damage Leydig cells per Dr. John's HCG statement that a dose greater than 500 IU at one time causes Leydig cell desensitivity.

They have fertility program in mind.
From what I gather, higher HCG doses over prolonged time did not impair testicular testosterone production of at least one felow (colkurtz_spf) who reports on AM board.

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post #79
http://anabolicminds.com/forum/male-anti-aging/66268-jans-bloodtest-april13-3.html