View Full Version : HCG expiration theory
hardasnails1973
12-09-2007, 11:32 AM
There has been some debate over when is hcg not effective. Well I have came up with my own theory. People with adrenal/thyroid issues tend to feel the effects start to lessening with in 21 to 25 days. Now you ask me how I know this. Well being on an AI + hcg + test every thing is in a fine balance. but after 21 days if one is hcg sensitive (increasing e2 from normal base line rapidly) and it becomes less potent and they are taking an anti estrogen in the first place this will cause a signifcant drop in e2resulting in experecning the hotflashes, mood swings, no morning wood joint pains and brain fog. This drop in hcg is also a stimulation for the adrenals so not only does one have low e2 but adrenal out put is lowered. Now for people with non adrenal issues they will not feel the effects as much and can use hcg past the 30 day mark and have no problems at all. I think alot of people expereince this but really never understood what was going on, but I think this may shed alittle more light on things. It even says on the bottle 30 days discard it. Why don't the manufactor make it in 2000 ius or may be they do but it has to be special ordered because 10,000 ius is a waste. Don;t you guys agree
Seems reasonable to me.
How about refrigerating your bac water before mixing the HCG up on day 1? Then you'd have an instantly cold mixture of fresh HCG vs waiting for 4 hrs for it to cool down in the fridge. I gotta think that we're losing some of its potency during that time.
Sonny
hardasnails1973
12-09-2007, 11:01 PM
bacteria static water does not have to be refrigerated. Once reconsituited with hcg or gh then it needs to be in fridge . I pop that stuff in there ASAP ..
Bill-NJ
12-10-2007, 09:20 AM
There has been some debate over when is hcg not effective. Well I have came up with my own theory. People with adrenal/thyroid issues tend to feel the effects start to lessening with in 21 to 25 days. Now you ask me how I know this. Well being on an AI + hcg + test every thing is in a fine balance. but after 21 days if one is hcg sensitive (increasing e2 from normal base line rapidly) and it becomes less potent and they are taking an anti estrogen in the first place this will cause a signifcant drop in e2resulting in experecning the hotflashes, mood swings, no morning wood joint pains and brain fog. This drop in hcg is also a stimulation for the adrenals so not only does one have low e2 but adrenal out put is lowered. Now for people with non adrenal issues they will not feel the effects as much and can use hcg past the 30 day mark and have no problems at all. I think alot of people expereince this but really never understood what was going on, but I think this may shed alittle more light on things. It even says on the bottle 30 days discard it. Why don't the manufactor make it in 2000 ius or may be they do but it has to be special ordered because 10,000 ius is a waste. Don;t you guys agree
My current TRT protocal ... (which I am following until I see Dr John) has me doing 250iu daily and I do notice towrards the end of vial 20 days I do not feel the same as I do at the start
Jaydee
12-10-2007, 09:46 AM
bacteria static water does not have to be refrigerated. Once reconsituited with hcg or gh then it needs to be in fridge . I pop that stuff in there ASAP ..
Will it hurt if you keep it in the fridge? Thats what im doing with mine. I debated over this and decided the fridge would be best for a re-usable BAC vial to keep it clean.
Charlie
12-10-2007, 12:41 PM
I have heard of freezing a portion of the 10,000 iu's until needed. Sounds like this would be at least worth a try instead of wasting the remainder of whats left after 30 or even 60 days.
hardasnails1973
12-10-2007, 12:49 PM
i think you be risking destabiliation of the powder..i need to research this further...
mixed reviews to be on safe side just toss it out and get a fresh one since insurance probably covers it in the first place
The hcg molecule isnt stable and there is nothing that you can do about it other than keep it cool and dark. Freezing will probably do more damage than good but the closer you get to 32 F the slower the decomposition. If you could know the rate of decomposition over time at the storage temperature the doseage could be adjusted to compensate of the loss of potency.
hardasnails1973
12-10-2007, 01:31 PM
I think people stress them selves out trying to examine every little detail.
Just use it for 20-30 days then toss it. Get a new one end of story ..majority of people on TRT have insurance any way so its not that big of a deal.. If you have a buddy that is on TRT split it and split the costs. That be the logical thing to do. Be suprised how many guys on the gym on TRT or better off how many went back to their drs for further evaluatons and got help they needed and it improved quality of life dramatically
Jaydee
12-10-2007, 01:59 PM
It says on this site not to freeze it.
"How should you store Pregnyl?
Pregnyl should be stored at 2 to 8°C. Do not freeze. Keep the ampoules in the outer container to protect from light. Do not use after the 'use by' date on the pack. Keep the ampoules in the original package in a safe place where children cannot reach them."
http://xpil.medicines.org.uk/ViewPil.aspx?DocID=8230
This has got to be one of the more comprehensive HGC information sites ive come across.
I agree with HAN. I dont think its worth the risk of it going bad to save a few bucks.
pmgamer18
12-10-2007, 03:16 PM
Yes what you think you saving today you can end up paying a lot down the road.
It says on this site not to freeze it.
"How should you store Pregnyl?
Pregnyl should be stored at 2 to 8°C. Do not freeze. Keep the ampoules in the outer container to protect from light. Do not use after the 'use by' date on the pack. Keep the ampoules in the original package in a safe place where children cannot reach them."
http://xpil.medicines.org.uk/ViewPil.aspx?DocID=8230
This has got to be one of the more comprehensive HGC information sites ive come across.
I agree with HAN. I dont think its worth the risk of it going bad to save a few bucks.
I dont like wasting shit. I`d shoot it up before throwing it out.
hardasnails1973
12-10-2007, 06:45 PM
10,000 ius in one month is alot of hcg if on trt. :eek:
I think the damn edit button is the qoute button ..
10,000 ius in one month is alot of hcg if on trt. :eek:
I think the damn edit button is the qoute button ..
Sure looks that way.
I dont mind getting into the anabolic range every so often. Kinda like it. It just like everything else- just dont wanna make a career out of it.
Wise Guy
12-10-2007, 10:04 PM
Sure looks that way.
I dont mind getting into the anabolic range every so often. Kinda like it. It just like everything else- just dont wanna make a career out of it.
Keep it under 500IU per day and watch E2
JanSz
12-11-2007, 11:48 AM
It says on this site not to freeze it.
"How should you store Pregnyl?
Pregnyl should be stored at 2 to 8°C. Do not freeze. Keep the ampoules in the outer container to protect from light. Do not use after the 'use by' date on the pack. Keep the ampoules in the original package in a safe place where children cannot reach them."
http://xpil.medicines.org.uk/ViewPil.aspx?DocID=8230
This has got to be one of the more comprehensive HGC information sites ive come across.
I agree with HAN. I dont think its worth the risk of it going bad to save a few bucks.
This is excellent piece of info, thank you.
===============================================
Pregnyl® 1500 I.U.
Pregnyl comes as 2 ml ampoules of dry white powder with 1 ml ampoule of solvent.
===============================================
Pregnyl® 5000 I.U.
Pregnyl comes as 2 ml ampoules of dry white powder with 1 ml ampoule of solvent.
===============================================
Note, both 1500iu and 5000iu
come with 1mL of solvent
===============================================
I am expecting the 1500 version to arrive, hopefully soon.
That would be 6 doses, 100/6=~16.5units each to make 250iu dose
But I am trying my 380iu dose.
explanation on bottom of my post #62 here:
http://anabolicminds.com/forum/male-anti-aging/66268-jans-bloodtest-april13-3.html
if I divide 1500 into 4 doses, 1500/4=375
or most likely slightly less due to spilage.
each dose 25units on insuline syringe.
=================================================
If the supply of 1500 Pregnyl is reliable, I may like it more than the Novarel.
I will be dealing with fresh product all the time.
=================================================
Question, what is the shelf life of unopened Pregnyl.
Looking at my old Novarel box, It looks like it is under a year.
Charlie
12-11-2007, 12:31 PM
Pregnyl ?
We started out talking about HCG !
What did I miss?
hardasnails1973
12-11-2007, 12:40 PM
pregnyl = hcg in european and mexican pharmacy
Charlie
12-11-2007, 12:48 PM
Thanks Hard Guy.
matttaylor
01-11-2009, 02:54 PM
GLAD i FOUND THIS THREAD BEFORE STARTING A NEW ONE. Helps to read the directions
'' look for old thread before starting new thread''
I just mixed a batch of HCG , and at current dosing 250 x 2 days a week, the vial last for months, well beyond shelf life of 30 days . I use it till its done instead of wasting it, but I think the HCG i not effecrive beyond two months
I think the best way to handle this is to have my compound pharmacy take the dried powder and separate it to maybe five vials. This way I add the mixing water to the vial I need that will give me a four week batch.
In other words, separate the powder to different batches, shelf life started once the mixing water is added. When that batchs gone, start another compounded vial, so on so on. Always fresh HGC on hand, no waste
4aminsomniac
01-11-2009, 05:29 PM
HAN,
You say most of us have insurance, I thought most insurance didn't cover HCG?
If UHC does, someone let me know, I am on a HSA Open plan, would be nice to get that covered if possible.
PhoneMonkey
01-11-2009, 06:24 PM
So, I’m a bone head… I’m so glad I came across this forum, wish I would have found it earlier.
Short version is I used 10,000 units of HCG over 5 weeks and left it at room temperature – nothing in the literature I got about refrigerating it but I went and dug out the tiny little insert in the box itself (had to use a magnifying glass to read it!) and sure enough, right there in 3 point font… bit of a noob move to be sure.
Anyway, I reconstituted a vial this morning and used on dose and left it out until I read this thread when I popped it in the fridge straight away – it’s been out about, oh, 8 or 9 hours or so – any thoughts on how fast HCG breaks down at room temperature after you add the water?
Also, I notice a number of post out here that recommend 500 u of HCG when using it with TRT – the instructions I got were 1 cc of T on Monday and 1000 units of HCG on the 6th and 7th day (two days before and day before next T shot). Hence the 10,000 unit bottle lasts 5 weeks – does that sound like too much for that type of program? I guess at this point I should probably “jump start” with some fresh HCG (I have an unconstituted bottle still) since I’ve been going 6 weeks now with basically no HCG while taking T injections. Any thoughts on how big a deal that is?
Thanks much – this forum looks to be loaded with a ton of good info…
medgerton
01-11-2009, 06:59 PM
So, I’m a bone head… I’m so glad I came across this forum, wish I would have found it earlier.
Short version is I used 10,000 units of HCG over 5 weeks and left it at room temperature – nothing in the literature I got about refrigerating it but I went and dug out the tiny little insert in the box itself (had to use a magnifying glass to read it!) and sure enough, right there in 3 point font… bit of a noob move to be sure.
Anyway, I reconstituted a vial this morning and used on dose and left it out until I read this thread when I popped it in the fridge straight away – it’s been out about, oh, 8 or 9 hours or so – any thoughts on how fast HCG breaks down at room temperature after you add the water?
Also, I notice a number of post out here that recommend 500 u of HCG when using it with TRT – the instructions I got were 1 cc of T on Monday and 1000 units of HCG on the 6th and 7th day (two days before and day before next T shot). Hence the 10,000 unit bottle lasts 5 weeks – does that sound like too much for that type of program? I guess at this point I should probably “jump start” with some fresh HCG (I have an unconstituted bottle still) since I’ve been going 6 weeks now with basically no HCG while taking T injections. Any thoughts on how big a deal that is?
Thanks much – this forum looks to be loaded with a ton of good info…
So you are using 2000 IU per week on average. Take a look at the sticky on HCG at the top of the threads page. You will see that Dr. John recommends no more than 500 IU at any one time. A lot of guys use about 250 IU twice per week that are on shots. On TD gel it is 200 IU EOD or 100 IU everyday.
Go ahead and read that sticky. You will see a discussion of the benefits of HCG in TRT. Good luck with your TRT.
medgerton
01-11-2009, 07:09 PM
HAN,
You say most of us have insurance, I thought most insurance didn't cover HCG?
If UHC does, someone let me know, I am on a HSA Open plan, would be nice to get that covered if possible.
If you mean United Health Care - I know how I got it covered. It took me about a month to figure it out.
Must use the CVS CareMark Specialty Pharmacy. They mail the drugs to you.
Now the tricky part. The pharmacy must charge it against your durable medical component of your plan. Yes, that is odd. Durable medical is for things like walkers/wheelchairs/oxygen tanks etc. It works for me.
I have phone numbers and ICD-9 codes if you want them. Let me know.
PhoneMonkey
01-11-2009, 08:30 PM
yeah - read through Dr. Crisler's doc and a bunch of posts here and elsewhere - I plan totry 500 units instead - of course that means one vial will last 10 weeks which is beyond the expiration time *sigh*.
I wish there were a way I could tell if the vial I left out for the day were still any good - hate to burn a nearly full vial when I didn't need to.
simpsonfan
01-13-2009, 06:28 PM
Am I missing something... My package insert for my HCG says it is good for 60 days. Thats 8-9 weeks.
PhoneMonkey
01-13-2009, 09:56 PM
but if you're taking 250 twice a week (500 a week) then that 10,000 unit bottle lasts 20 weeks... even if the 60 days is conservative (I'm sure it must be) that's quite a ways outside the range - gotta think by the end of that you're shooting basically water. I'd be nice if I could get smaller units but the guys I'm going through say 10,000 is all they use.
matttaylor
01-13-2009, 10:23 PM
I still think the answer is to cut the pwder into half doses, add the mixing water to 1/2 the powder in one month, followed by the second batch of powder when needed.
The mixing water does not expire as long as kep cold, HCG expiration time start when the powder and and mixing water are mixed
PhoneMonkey
01-13-2009, 11:55 PM
not sure how to cut the powder in half - mine comes in a sealed jar - guess I could get other jars somewhere, tear it open and cut it in half - not real sure where to get such equipment, though. Might be worth the trouble as opposed to shooting less effective medication near the end of it's life though.
4aminsomniac
01-14-2009, 10:46 AM
I dont like wasting shit. I`d shoot it up before throwing it out.
Really? I have a thread about HCG bad reactions...search for it.
After about 4-5 weeks, I started to get an allergic reaction to the HCG I had been using. There are many possible causes. But, I didn't have a problem the first 3 weeks of use. Then come week 5-6, it started to cause my eosonophilic esophogitis to act up causing my throat to swell, have a constricted feeling and allergic reaction to the stuff after it went bad.
Haven't use any HCG for almost 2 weeks now, and the issue has resolved itself. So HAN's theory also applies to possible changes in the HCG that can cause issues for some people, like myself after a certain peroid of time. Not just adrenal etc..
Shooting stuff in your body just because you don't want waste is a short sighted and possibly dangerous proposition for some. It literally could have causes an allergic reaction that could have caused my throat to close up and only an EPI pen could have saved my life.
Fortunately, it was a mild reaction to my throat, and face flushing and I didn't need any emergency EGD or help.
Just something to consider.
Dr. John Crisler
01-14-2009, 08:07 PM
But people are on it constantly.
There has been some debate over when is hcg not effective. Well I have came up with my own theory. People with adrenal/thyroid issues tend to feel the effects start to lessening with in 21 to 25 days. Now you ask me how I know this. Well being on an AI + hcg + test every thing is in a fine balance. but after 21 days if one is hcg sensitive (increasing e2 from normal base line rapidly) and it becomes less potent and they are taking an anti estrogen in the first place this will cause a signifcant drop in e2resulting in experecning the hotflashes, mood swings, no morning wood joint pains and brain fog. This drop in hcg is also a stimulation for the adrenals so not only does one have low e2 but adrenal out put is lowered. Now for people with non adrenal issues they will not feel the effects as much and can use hcg past the 30 day mark and have no problems at all. I think alot of people expereince this but really never understood what was going on, but I think this may shed alittle more light on things. It even says on the bottle 30 days discard it. Why don't the manufactor make it in 2000 ius or may be they do but it has to be special ordered because 10,000 ius is a waste. Don;t you guys agree
Dr. John Crisler
01-14-2009, 08:08 PM
bacteria static water does not have to be refrigerated. Once reconsituited with hcg or gh then it needs to be in fridge . I pop that stuff in there ASAP ..
It certainly does!
It's the temp that breaks down the peptide chain.
Dr. John Crisler
01-14-2009, 08:09 PM
I have heard of freezing a portion of the 10,000 iu's until needed. Sounds like this would be at least worth a try instead of wasting the remainder of whats left after 30 or even 60 days.
You are not supposed to freezre it once reconstituted.
wondering
01-14-2009, 09:28 PM
Dr. Crisler.. are you saying we should refrigerate the water before reconstituting the HCG.
It certainly does!
It's the temp that breaks down the peptide chain.
4aminsomniac
01-15-2009, 08:18 AM
I hope that bacteriostaic water doesn't have to be refrigerated. Since it doesn't say that on the bottle I have left mine at room temp. for the past few months. I wonder if that has made my HCG less effective?
Yeah, if that is the case, I would say almost all of us have bottles sitting at room temperature waiting to be mixed that could be a waste of money and down the toilet now?
That isn't good if that is true and nobody has said this before.
4aminsomniac
01-17-2009, 11:00 AM
Bump this up for an answer.
Are you supposed to refrigerate the bac water when received and leave it in the fridge for months until it is needed and mixing?
Or is it alright to leave it at room temperature while you wait to mix.
Several have asked this question in this thread. Dr. J said you refrigerate.
But this is the first I have heard of that and my instructions didn't say to refrigerate before mixing while you are waiting to use it months down the road.
My fear of course if that my HCG is worthless now that I haven't mixed yet due to having non-refrigerated bac water sitting room temp/dark location.
Thanks
medgerton
01-17-2009, 01:39 PM
Bump this up for an answer.
Are you supposed to refrigerate the bac water when received and leave it in the fridge for months until it is needed and mixing?
Or is it alright to leave it at room temperature while you wait to mix.
Several have asked this question in this thread. Dr. J said you refrigerate.
But this is the first I have heard of that and my instructions didn't say to refrigerate before mixing while you are waiting to use it months down the road.
My fear of course if that my HCG is worthless now that I haven't mixed yet due to having non-refrigerated bac water sitting room temp/dark location.
Thanks
I am pretty sure that he meant refrigerate after mixing. There is no peptide chain in only the water. The water doesn't need to be refrigerated.
The way Novarel comes it has a bottle of water and a vile of powder. so I get new water everytime I get new powder. So I through away the unused water after mixing and never store the water anyways.
4aminsomniac
01-17-2009, 04:22 PM
I am pretty sure that he meant refrigerate after mixing. There is no peptide chain in only the water. The water doesn't need to be refrigerated.
The way Novarel comes it has a bottle of water and a vile of powder. so I get new water everytime I get new powder. So I through away the unused water after mixing and never store the water anyways.
I agree, that is what the instructions from the pharma says also, after reconstitution, refrigerate.
living2die
02-21-2009, 12:22 AM
Bill,
I pretty much find myself in the same sad state of affairs that you do in regard to hcg. after the 20 day mark (i am using Pregnyl at 500IU EOD monotherapy) i find that the positive response that i enjoyed at the beginning of the vial has dissipated.
from now on, i will reconstitute the 5000IU pregnyl amp as per what i normally do, and split the dosage in half, with 2500IU going in a slin pin for storage in the freezer and the other 2500IU i will store in the fridge for immediate use. i used to have a study i would consult, which stated that hcg will not degrade if sent through a single freeze cycle...it is the multiple freeze/thaw cycles that degrade potency.
do you freeze your hcg for maximum economy?
My current TRT protocal ... (which I am following until I see Dr John) has me doing 250iu daily and I do notice towrards the end of vial 20 days I do not feel the same as I do at the start
hardasnails1973
02-21-2009, 12:28 AM
Bill,
I pretty much find myself in the same sad state of affairs that you do in regard to hcg. after the 20 day mark (i am using Pregnyl at 500IU EOD monotherapy) i find that the positive response that i enjoyed at the beginning of the vial has dissipated.
from now on, i will reconstitute the 5000IU pregnyl amp as per what i normally do, and split the dosage in half, with 2500IU going in a slin pin for storage in the freezer and the other 2500IU i will store in the fridge for immediate use. i used to have a study i would consult, which stated that hcg will not degrade if sent through a single freeze cycle...it is the multiple freeze/thaw cycles that degrade potency.
do you freeze your hcg for maximum economy?
When this occurs it is mostly adrenal related.
living2die
02-21-2009, 01:14 AM
HAN i dont get it though...why do i feel good again when i start a new batch, stored under the exact same conditions as the last batch, as well as all other variables replicated to the T ?
When this occurs it is mostly adrenal related.
hardasnails1973
02-21-2009, 01:45 AM
Dr J commented that it depends on a person bioindiviudality (their chemistry) on how they respond to drugs. Alot of guys that have this issue have adrenal imbalance and it may bulid up a tolerance or desensitize them to the HCG some how..
living2die
02-21-2009, 03:35 AM
HAN are you saying that our body undergoes a psychosomatic transformation between day 1 and day 20 of our hcg scheduling, and from 20 days onwards becomes increasingly severe, but as soon as the cycle begins anew with day 1 of a fresh hcg ampule, the psychosomatic ailment goes back into remission?
i think your theory asserted at the beginning of this thread makes more sense than dr. john's imo
Dr J commented that it depends on a person bioindiviudality (their chemistry) on how they respond to drugs. Alot of guys that have this issue have adrenal imbalance and it may bulid up a tolerance or desensitize them to the HCG some how..
chilln
02-21-2009, 07:53 AM
HAN are you saying that our body undergoes a psychosomatic transformation between day 1 and day 20 of our hcg scheduling, and from 20 days onwards becomes increasingly severe, but as soon as the cycle begins anew with day 1 of a fresh hcg ampule, the psychosomatic ailment goes back into remission?
i think your theory asserted at the beginning of this thread makes more sense than dr. john's imo
Sorry HAN and living2die. This theory is completely bogus.
That simply because this theory is irrelevant with Ovidrel.
Ovidrel is recombinant HCG, with no urine impurities, it last months in the fridge.
I buy three syringes at a time, and I put all three in the fridge on the same day.
I inject half a syringe into 2.5 mL of water-for-injection (ie: water + saline only, not bacteriostatic water), and I use that up over 20 days.
Then I inject the other half of the Ovidrel syringe into a fresh batch of 2.5 mL of water-for-injection (ie: water + saline only, not bacteriostatic water), and use that up over another 20 days.
Each Ovidrel syringe lasts me 40 days.
I never ever ever ever notice any change in efficacy from one syringe to the next, or from one day to the next.
###
What's happening to urinary derived HCG, is that the urinary impurities are causing degradation.
Simple as that.
As soon as you switch to the pure stuff there's no change in efficacy - not even after 120 days in the refrigerator.
###
If you experience problems with urinary derived HCG, then please switch to Ovidrel.
Dr. John Crisler
02-21-2009, 09:22 AM
Well done, sir.
The hcg molecule isnt stable and there is nothing that you can do about it other than keep it cool and dark. Freezing will probably do more damage than good but the closer you get to 32 F the slower the decomposition. If you could know the rate of decomposition over time at the storage temperature the doseage could be adjusted to compensate of the loss of potency.
hardasnails1973
02-21-2009, 09:33 AM
I have used every brand of HCG other then ovidel and I find this happens to alot of people. It comes down to peoples body metabolism drugs different plain and simple. Just because it works for one person it may not respond the same to another.. That is just plain facts of any medical drug and the human body. Give a person 100 mgs of testosterone each have identical serums you can get to total differnt responses. There are just too many biological variables that are work to say one type of drug is going to have an identical reaction to every one. The idea of bioindividuality is the proper answer as dr J pointed out long ago in this thread.
living2die
02-21-2009, 05:47 PM
one might also surmise that the hrt protocol influences the debatable loss of hcg's potency around the 21 day mark. if one were on a hcg monotherapy, and the hcg were to become degraded in any manner, one wouldnt have exo T to fall back on. a small decline in T could have a pronounced subjective psychosomatic effective on the hcg monotherapy goer vs. the T + HCG goer who would at least the TT boosting effective of exo T, which might diminish the perceptibility of hcg's loss of potency.
I have used every brand of HCG other then ovidel and I find this happens to alot of people. It comes down to peoples body metabolism drugs different plain and simple. Just because it works for one person it may not respond the same to another.. That is just plain facts of any medical drug and the human body. Give a person 100 mgs of testosterone each have identical serums you can get to total differnt responses. There are just too many biological variables that are work to say one type of drug is going to have an identical reaction to every one. The idea of bioindividuality is the proper answer as dr J pointed out long ago in this thread.
chilln
02-21-2009, 06:39 PM
I have used every brand of HCG other then ovidel and I find this happens to alot of people.
No stress. Switch to Ovidrel for a while and discover what the rest of us who use Ovidrel already know.
It comes down to peoples body metabolism drugs different plain and simple. Just because it works for one person it may not respond the same to another.. That is just plain facts of any medical drug and the human body. Give a person 100 mgs of testosterone each have identical serums you can get to total differnt responses. There are just too many biological variables that are work to say one type of drug is going to have an identical reaction to every one. The idea of bioindividuality is the proper answer as dr J pointed out long ago in this thread.
If a person's response to boosted hormones is a moving target, then that's most likely because:
a) they're messing with their dosages without a reasonable knowledge of the consequences
or
b) their body hasn't yet adjusted to the availability of the hormones, and it is still adapting in a noticeable way (over a period of 20 days)
or
c) they live a lifestyle with widely varying physical and mental stressors, and they haven't worked out how to modify their dosages accordingly, eg: by switching to daily dosing dosing instead of weekly dosing.
or
d) In the specific case of HCG, the urinary impurities in HCG will take their toll on urinary derived HCG, but recombinant derived HCG takes a LOT longer to degrade, when handled the same as urinary derived HCG.
hardasnails1973
02-21-2009, 07:33 PM
I found a simple solution
On script dr puts
"use as directed discard after 3 weeks"
:thumbup:
living2die
02-21-2009, 08:03 PM
chilln,
i think the clincher for me is D. makes sense and is logical. i hope that ovidrel loses its patent in a few years so that more pharm's can develop their own brands of rHCG to make it more inexpensive. also, maybe b/c each amp of urinary derived hcg comes from the collection of unknown x amount of pregnant females, the body develops somewhat of a tolerance to specific batch of hcg. when a new amp is started, the fingerprint of hcg contained within the hcg will likely be collected from the urine of a different population group of pregnant females.
No stress. Switch to Ovidrel for a while and discover what the rest of us who use Ovidrel already know.
If a person's response to boosted hormones is a moving target, then that's most likely because:
a) they're messing with their dosages without a reasonable knowledge of the consequences
or
b) their body hasn't yet adjusted to the availability of the hormones, and it is still adapting in a noticeable way (over a period of 20 days)
or
c) they live a lifestyle with widely varying physical and mental stressors, and they haven't worked out how to modify their dosages accordingly, eg: by switching to daily dosing dosing instead of weekly dosing.
or
d) In the specific case of HCG, the urinary impurities in HCG will take their toll on urinary derived HCG, but recombinant derived HCG takes a LOT longer to degrade, when handled the same as urinary derived HCG.
living2die
02-21-2009, 09:30 PM
SWEET. Thanks HAN. this factoid is good, because it proves that those (including myself) who claim the potency of hcg dwindles after 21 days might not be basket cases after all.
Just to clarify, your doctor writes this on your own personal script, of you have heard of this being done on an acquittance of yours?
I found a simple solution
On script dr puts
"use as directed discard after 3 weeks"
:thumbup:
ZonaDave
02-21-2009, 10:36 PM
i just mix up a new batch, put it in individual syringes and freeze it. take it out 10 minutes before use and it's good to go!