HCG Mono... degree of efficacy and realistic long term?

[Dadnatron]

I have been reading for quite some time about HCG used as monotherapy in younger men with low T. I have also read countless back and forth (YES/NO) forums and articles on whether it is something which will be realistic long term.

So, although it has been stated before, I am going to ask it again, hopefully with more updated information and thoughts in this thread.

IS HCG a reasonable monotherapy long term in a younger man? (Understanding that if it works ie gets T to say... 800)

Are there any known issues utilizing HCG long term in such a manner?

Understanding that it is typically utilized more for cosmesis in TRT patients, what seems to be the outcome as a monotherapy?

I ask because should things progress, it is likely that I will be on SOME FORM of Testosterone enhancement be that direct replacement (2nd choice) or via endogenous stimulation (1st choice).

I am drawn toward simply beginning with HCG. However, when I brought this up with my new AA doc, he questioned its utility and said we would typically use Clomid. I don't know whether he thought I meant simply a 'restart' or long term.

If I did choose to simply try a 'Clomid' restart, as he might suggest, does anyone have a link to information concerning how it is instituted? Or does anyone have any thoughts and articles on it?

I guess what it all comes down to is that I would like my T levels to be MUCH better, perhaps 800-1000 depending upon how I feel obviously. And I am unsure how to get there at age 41 with the LEAST direct supplementation. I would like to keep my HTPA doing as much of the work as possible.

[Dadnatron]

This is from John's 2007 HCG update:


While HCG, as sole TRT, is still considered treatment of choice for hypogonadotrophic hypogonadism by many , my experience is that it just does not bring the same subjective benefits as pure testosterone delivery systems do—even when similar serum androgen levels are produced from comparable baseline values. However, supplementing the more “traditional” TRT of transdermal, or injected, testosterone with HCG stabilizes serum levels, prevents testicular atrophy, helps rebalance expression of other hormones, and brings reports of greatly increased sense of well-being and libido. My patients absolutely love it. As time goes on, we are coming to appreciate HCG as a much more powerful--and wonderful--hormone than previously given credit.

[cpeil2]

I have been reading for quite some time about HCG used as monotherapy in younger men with low T. I have also read countless back and forth (YES/NO) forums and articles on whether it is something which will be realistic long term.

So, although it has been stated before, I am going to ask it again, hopefully with more updated information and thoughts in this thread.

IS HCG a reasonable monotherapy long term in a younger man? (Understanding that if it works ie gets T to say... 800)

Are there any known issues utilizing HCG long term in such a manner?

Understanding that it is typically utilized more for cosmesis in TRT patients, what seems to be the outcome as a monotherapy?

I ask because should things progress, it is likely that I will be on SOME FORM of Testosterone enhancement be that direct replacement (2nd choice) or via endogenous stimulation (1st choice).

I am drawn toward simply beginning with HCG. However, when I brought this up with my new AA doc, he questioned its utility and said we would typically use Clomid. I don't know whether he thought I meant simply a 'restart' or long term.

If I did choose to simply try a 'Clomid' restart, as he might suggest, does anyone have a link to information concerning how it is instituted? Or does anyone have any thoughts and articles on it?

I guess what it all comes down to is that I would like my T levels to be MUCH better, perhaps 800-1000 depending upon how I feel obviously. And I am unsure how to get there at age 41 with the LEAST direct supplementation. I would like to keep my HTPA doing as much of the work as possible.

Send Leanguy a PM. He is using hCG monotherapy with excellent results. I think he's a little younger than you are, though.

[JanSz]

You are trying to make your own GH.

Consider making your own LH & FSH

===================================

U-opiod antagonists to prevent HPTA suppression, and pituitary atrophy

http://musclechatroom.com/forum/showthread.php?t=2603


If you go this way, please start new thread dedicated to that topic only.
It is not very well researched but promising way of doing TRT.
===================================

Otherwise;

start with

always fresh (HCG)

HCG-shot=250iu/EOD

and do not go above (about) 650iu/EOD

Your sweet spot will be a size of HCG-shot that would not require excessive Arimidex supplementation.

max Arimidex=1.5mg/week
================================

If you are able ($$$)(otherwise a first choice);

Do
HMG-shot=75iu/EOD

and then
additional HCG shots (again constrained by Arimidex requirements)


===================================
You may want to look at my post #62
http://anabolicminds.com/forum/male-anti-aging/66268-jans-bloodtest-april13-3.html

Picture on the bottom.
plus referenced research.

It appears that HCG=306iu/EOD should be "ideal" theoretical dose.
Per observation by others, testicle can be "boosted" to about 140% of their "nominal" capacity at the time.

Equation I developed and the chart, indicate that after (about) 600iu/EOD
any further boosting is not effective.

......
There are Cenegenic patients that try to go beyond that limit with erratic results.


.....

[Dadnatron]

Hmg?

[thelordhumungus]

hMG is a combination of LH, FSH, and hCG. It provides a closer match to your bodies own hormones. hCG simulates LH or FSH (I forget which) in your body but is not exactly identical so hMG is a closer match.

[chilln]

I have been reading for quite some time about HCG used as monotherapy in younger men with low T. I have also read countless back and forth (YES/NO) forums and articles on whether it is something which will be realistic long term.

So, although it has been stated before, I am going to ask it again, hopefully with more updated information and thoughts in this thread.

IS HCG a reasonable monotherapy long term in a younger man? (Understanding that if it works ie gets T to say... 800)


Depends on the rest of this person's hormone mileau. No-one should ever answer "yes" or "no" to this question without first considering the state of the persons main hormones, aside from T (testosterone).

Unfortunately there are far too many variables to summarize, in a simple forum post, even the main solution options, for the main problem types which we see regularly.

On the other hand, it's definitely possible to discuss this with respect to your specific hormone profile (if you have a reasonable set of labs), plus a discussion of your symptoms, and any past therapeutic testing (dosage-response trials) you may have already done.





Are there any known issues utilizing HCG long term in such a manner?

Understanding that it is typically utilized more for cosmesis in TRT patients


While HCG may be marketed that way to some patients with less understanding of hormones, HCG's testicle hormone boost impact has health benefits which I consider to be at least equal to the cosmetic benefits, over decades of use.

The health benefits are that the testicles produce other hormones apart from testosterone, at significant levels, and if we allow our testicles to atrophy, we must then backfill the these hormones by the amounts lost as a result of their atrophy.

This was discussed with reasonable precision here:

http://musclechatroom.com/forum/showpost.php?p=56533&postcount=44



I am drawn toward simply beginning with HCG. However, when I brought this up with my new AA doc, he questioned its utility and said we would typically use Clomid. I don't know whether he thought I meant simply a 'restart' or long term.


I suspect he may have meant using Clomid as TRT indefinitely. You need to find out. Ask him / her.

We do not recommend using Clomid or Tamoxifen (or any other SERM) as any part of a long term male hormone modulation therapy, as discussed here:

http://musclechatroom.com/forum/showpost.php?p=71374&postcount=7

###

BB forums (dangerously unhealthy places) list restart protocols, but most cannot be trusted.

None of the male hormone therapy doctors have made publicly available any documentation of their restart protocols.
A significant part of Dr Crisler's business is restarts. I'm not sure he's going to part with his restart protocol in a hurry.

We are not allowed to recommend any form of therapy on this forum. We can provide biology info, or info about supps, but we cannot invent a therapy for you. We can help you tweak a therapy which has been provided to you by a medical professional adviser.

.

[LeanGuy]

HCG mono is working well for me (I am 35)... my TT levels have been consistently at 800-900 by injecting 200iu EOD. I use a little T gel but this is for DHT mainly. I also take .25mg arimidex 2x week to control E2.

At 400iu EOD it worked too well... TT=1400 and E2=90... yikes

HMG = too expensive.

[GirlyMan]

IS HCG a reasonable monotherapy long term in a younger man? (Understanding that if it works ie gets T to say... 800)

Dunno. But I do know that at some point the fellas are gonna stop showing up for work. At that point we rub the lotion on the skin or else we get the hose again.

[LowT]

I'll just chime in as a young guy (30) that tried hCG mono and got my numbers up to a good range but still felt like crap compared to using gel or injections.

Why? Who knows.

[thelordhumungus]

Dunno. But I do know that at some point the fellas are gonna stop showing up for work. At that point we rub the lotion on the skin or else we get the hose again.

Haha wow, that won my first hearty laugh of the day.

[cpeil2]

Hmg? Human menopausal gonadotropin.

[Dadnatron]

I'll just chime in as a young guy (30) that tried hCG mono and got my numbers up to a good range but still felt like crap compared to using gel or injections.

Why? Who knows.

This is INCREDIBLY interesting. I have read this is sometimes the case. How is it that you found that TRT directly made you feel better? I would not have thought to supplement if my levels were where I wanted them.

Anyone ELSE have any experience with HCG - Mono not having the outcome in
'feeling' that you get on similar levels of direct TRT?

[Bulldog]

This is INCREDIBLY interesting. I have read this is sometimes the case. How is it that you found that TRT directly made you feel better? I would not have thought to supplement if my levels were where I wanted them.

Anyone ELSE have any experience with HCG - Mono not having the outcome in
'feeling' that you get on similar levels of direct TRT?

Dr. John mentions in his "TRT A Recipe For Success" paper that this is quite common.

[LowT]

This is INCREDIBLY interesting. I have read this is sometimes the case. How is it that you found that TRT directly made you feel better? I would not have thought to supplement if my levels were where I wanted them.

Anyone ELSE have any experience with HCG - Mono not having the outcome in
'feeling' that you get on similar levels of direct TRT?

Yes, this does not seem to be a unique experience.

On hCG mono I still had a good sex drive but my energy was nothing like being on gel or shots. My mood was notably lower as well. I never really suffered from depression but on TRT I noticed a marked improvement in my emotions and general feeling of well-being.

All the benefits of TRT minus the boost in libido went away on hcg mono. I still use hcg in combination with my other TRT though.

[Matty]

Keep in mind this is my opinion but,

The quote from Dr. John is bang on.

Also I swear HCG causes a higher affinity for aromatization especially in larger doses (which are required for HCG monotherapy).

[Matty]

PS Why are people so hellbent on avoiding TRT, and going HCG mono? It confuses me. With a bit of HCG your balls will be kept busy.

[LowT]

hcg mono is also extremely inconvenient as it has to be refrigerated at all times and dosed often.

If insurance is not involved it's also the most expensive.

[LeanGuy]

Dr. John mentions in his "TRT A Recipe For Success" paper that this is quite common.

What is the reason... Excess E2? Excess other hormones resulting from the stimulation of pregnenolone? It seems HCG would produce a more natural cascade than TRT and make you feel better.

[JanSz]

What is the reason... Excess E2? Excess other hormones resulting from the stimulation of pregnenolone? It seems HCG would produce a more natural cascade than TRT and make you feel better.

There are many casual claims, but

I am looking for a laundry list of hormones and other stuff that is produced by testicles
(plus a link to some relatively serious research to prove it).


...

[canthavetoomanytoys]

There are many casual claims, but
I am looking for a laundry list of hormones and other stuff that is produced by testicles
(plus a link to some relatively serious research to prove it).
...
Not exactly a scientific journal but here is something:

"Leydig cells release a class of hormones (http://www.answers.com/topic/hormone) called androgens (http://www.answers.com/topic/androgen) (19-carbon steroids (http://www.answers.com/topic/steroid)). They secrete testosterone (http://www.answers.com/topic/testosterone), androstenedione (http://www.answers.com/topic/androstenedione) and dehydroepiandrosterone (http://www.answers.com/topic/dhea) (DHEA), when stimulated by the pituitary (http://www.answers.com/topic/pituitary-gland) hormone luteinizing hormone (http://www.answers.com/topic/luteinizing-hormone) (LH). LH increases cholesterol (http://www.answers.com/topic/cholesterol) desmolase (http://www.answers.com/topic/cholesterol-side-chain-cleavage-enzyme) activity (an enzyme associated with the conversion of cholesterol (http://www.answers.com/topic/cholesterol) to pregnenolone (http://www.answers.com/topic/pregnenolone)), leading to testosterone synthesis and secretion by Leydig cells."
http://www.answers.com/topic/leydig-cell

[ptm82379]

hcg mono is also extremely inconvenient as it has to be refrigerated at all times and dosed often.

If insurance is not involved it's also the most expensive.

Not so much with Ovidrel

[JanSz]

Not exactly a scientific journal but here is something:

"Leydig cells release a class of hormones (http://www.answers.com/topic/hormone) called androgens (http://www.answers.com/topic/androgen) (19-carbon steroids (http://www.answers.com/topic/steroid)). They secrete testosterone (http://www.answers.com/topic/testosterone), androstenedione (http://www.answers.com/topic/androstenedione) and dehydroepiandrosterone (http://www.answers.com/topic/dhea) (DHEA), when stimulated by the pituitary (http://www.answers.com/topic/pituitary-gland) hormone luteinizing hormone (http://www.answers.com/topic/luteinizing-hormone) (LH). LH increases cholesterol (http://www.answers.com/topic/cholesterol) desmolase (http://www.answers.com/topic/cholesterol-side-chain-cleavage-enzyme) activity (an enzyme associated with the conversion of cholesterol (http://www.answers.com/topic/cholesterol) to pregnenolone (http://www.answers.com/topic/pregnenolone)), leading to testosterone synthesis and secretion by Leydig cells."
http://www.answers.com/topic/leydig-cell

Interesting.
We always worry about Estrodial E2, when increasing HCG.

I would expect E2 in prominent position in the list you posted.

...

[canthavetoomanytoys]

Interesting.
We always worry about Estrodial E2, when increasing HCG.

I would expect E2 in prominent position in the list you posted.

...

Is not the increased E2 as a result of the hCG driving testosterone higher which then aromatizes to a greater degree to E2?

[agoraphobe]

HCG mono is working well for me (I am 35)... my TT levels have been consistently at 800-900 by injecting 200iu EOD. I use a little T gel but this is for DHT mainly. I also take .25mg arimidex 2x week to control E2.

At 400iu EOD it worked too well... TT=1400 and E2=90... yikes

HMG = too expensive.

what brand of hcg are you using?

how much is hmg? (never heard of it before now!)

[LeanGuy]

Is not the increased E2 as a result of the hCG driving testosterone higher which then aromatizes to a greater degree to E2?

I believe HCG also stimulates aromatase directly


what brand of hcg are you using?

how much is hmg? (never heard of it before now!)

I use Pregynl brand HCG

HMG (Pergonal) = ~$250 for 75iu (not sure how much is typically used)



Maybe HCG mono kills FSH, causing some issues. But doesn't TRT also diminish FSH along with LH?

[agoraphobe]

What are some example well known protocols for monotherapy?

I've read shippen puts guys on daily HCG for the first 3 weeks to a month, with possibly weekends off?

Why do hcg every other day, instead of every day?

[JanSz]

I believe HCG also stimulates aromatase directly


Plausible hypothesis but having some kind of research would help.

...
In fertility protocol huge HCG doses are used.

I was disappointed when nobody worries about E2 in that kind protocol.

http://anabolicminds.com/forum/male-anti-aging/66268-jans-bloodtest-april13-3.html#post1332530

Picture at the bottom of post #79
-----

I think it was last year on meso board.
There was someone claiming to be a doc doing fertility protocols.

When I asked him, he was not able to figure out why should he worry about father's to be E2 (or even gyno).
Completely focused on ripping out a sperm from the guy and nothing else.

...

[agoraphobe]

What are some example well known protocols for monotherapy?

I've read shippen puts guys on daily HCG for the first 3 weeks to a month, with possibly weekends off?

Why do hcg every other day, instead of every day?

^bump for answer :biggrin: (if anyone knows)

[josh]

Anyone ELSE have any experience with HCG - Mono not having the outcome in 'feeling' that you get on similar levels of direct TRT?

I have not had the 'feeling' on cream, shots or hcg so far...

[LeanGuy]

I have not had the 'feeling' on cream, shots or hcg so far...

The "feeling" comes and goes for me... I can't figure out why, or how to make it last.

[seekonk]

Why do hcg every other day, instead of every day?

Because the serum HCG does not fall much over 2 days for doses up to 250 IU.

This graph:
http://jcem.endojournals.org/cgi/content/full/90/5/2595/F1

shows the difference between waiting 1 day (day 7) and waiting 2 days (day 14) to measure serum HcG. As you can see, there is not much difference for the typical dose of 250 IU.

[JanSz]

Because the serum HCG does not fall much over 2 days for doses up to 250 IU.

This graph:
http://jcem.endojournals.org/cgi/content/full/90/5/2595/F1

shows the difference between waiting 1 day (day 7) and waiting 2 days (day 14) to measure serum HcG. As you can see, there is not much difference for the typical dose of 250 IU.

That chart was based on:

"hCG was administered every other day, whereas serum hCG levels were measured once per week. "

========================

This chart indicates that after 7 days plateau is reached.
I have a little problem with that.

I do EOD HCG injections
and definitely feel consistency of my testicles fluctuating on EOD frequency,
from rather hard to mushy.

I am not going to change to ED injections, I do not feel any other than cosmetic drawbacks.

When I win lottery, I will possibly add HMG or switch completely to it.
.........

[thenxtgrt1]

The "feeling" comes and goes for me... I can't figure out why, or how to make it last.

The "feeling" comes and goes for me as well. My TRT experience hasn't been constant due to insurance difficulties, financial reasons, and other factors. Over the last two years, much of this has been corrected. I've been blessed.

I've been on HCG mono in the past and had test levels above range. But I don't think I stayed on long enough to realize any benefits. This was about a year and a half ago. For the last 5-6 months, I've used APP brand of HCG. I don't believe this to be effective as other brands. A few days ago I began Pregnyl, so we'll see how that goes. I throw in a little gel intermittently to keep DHT levels in the upper range.

Energy has never been huge problem for me. My main concerns are libido and erection quality. But as far as how to maintain the "feeling", for me it will probably come down to optimizing adrenals or thyroid. And minimizing stress.

[CubbieBlue]

What kind of protocol are you hcg mono folks using?

Care to share?

At one point I was on 2,000 IU 2 x a week w/ .5 mg arimidex M W F.

I did that for a month and then stopped to seek a second opinion.

I felt pretty good on that regimen though.

[LeanGuy]

What kind of protocol are you hcg mono folks using?


200iu EOD + .5mg adex E3D

Lately I feel like my E2 is high again... even on this low dose

[CubbieBlue]

Really? Odd. That is a pretty low dose. What are your levels like around that? If you get your estradiol tested soon please post your results, I am interested!

[LeanGuy]

Really? Odd. That is a pretty low dose. What are your levels like around that? If you get your estradiol tested soon please post your results, I am interested!

TT around 800-900 and E2 25-30

[thenxtgrt1]

What kind of protocol are you hcg mono folks using?

Care to share?

At one point I was on 2,000 IU 2 x a week w/ .5 mg arimidex M W F.

I did that for a month and then stopped to seek a second opinion.

I felt pretty good on that regimen though.


I'm currently on 500 iu E3D. Taking 0.25 mg of adex on injection days. Just began Pregnyl brand of hcg almost 2 weeks ago. Haven't had labs done yet, but I've been feeling pretty good as of lately. This could be due to a few other things plus I've been on a focused nootropic regimen.

[chilln]

I'll just chime in as a young guy (30) that tried hCG mono and got my numbers up to a good range but still felt like crap compared to using gel or injections.

Why? Who knows.

Had your medical professional adviser cared to modulate your E2 upwards and downwards (a therapeutic trial / dosage-response trial) to find a sweet spot, then I'll wager both he and you would have discovered the root cause.

The same post also explains how to locate the serious research articles for other testicular-manufactured hormones.

.

[chilln]

There are many casual claims, but

I am looking for a laundry list of hormones and other stuff that is produced by testicles
(plus a link to some relatively serious research to prove it).


...

The following is not a complete list, but references serious research, ie:

http://musclechatroom.com/forum/showpost.php?p=56533&postcount=44

[chilln]

This is INCREDIBLY interesting. I have read this is sometimes the case. How is it that you found that TRT directly made you feel better? I would not have thought to supplement if my levels were where I wanted them.

Anyone ELSE have any experience with HCG - Mono not having the outcome in
'feeling' that you get on similar levels of direct TRT?

What's incredibly interesting about LowT's case is that his medical professional adviser has such a poor understanding of male hormone modulation therapy.

As a result, LowT's ability to understand what happened is inadequate, and LowT's issue was never resolved.

That doesn't mean that LowT's issues are unresolvable, or cannot be understood.
In fact the contrary is the case. LowT's issues are resolvable, and can be understood - but not by LowT's medical professional adviser, and therefore not by LowT.

###

Just because LowT's medical professional adviser was poorly trained does not mean that HCG mono therapy was at fault.

Doctors should only prescribe therapy they understand, but clearly this is not the case.

The same applies to your medical professional adviser. If you're getting poor performance from HCG, or any of your hormone modulation supps, then you will need to switch to a different medical professional adviser.

If you believe you need to re-train your medical professional adviser, then good luck. If you can read the posts from others, and reliably predict which hormones is/are causing their symptoms, then you can do this.

But if you read the posts from others, and you are unable to reliably predict which hormones is/are causing their symptoms, then I doubt you'll be able to do this, and you'd be best switching medical professional advisers.

###

If you wish to try a different medical professional adviser in your locale, then let me know your locale, either via a post her or via a PM, and I'll PM you with some details.

.

[Dadnatron]

Has anyone ever tried HCG and seen no significant effect on numbers? I know that people have had less significant SUBJECTIVE effects in 'feeling' well, however, has anyone found that with HCG... their numbers simply didn't budge?

I finally got my Thyroid improved and began HCG a month ago. Novarel 250 iu M/W/F/S to 1000iu/wk. My test/bio did NOTHING, maybe up a few points, but well within normal measurment variance.

E2 is stable as well.

REALLY NOTHING happened at all to speak of...

[CubbieBlue]

Has anyone ever tried HCG and seen no significant effect on numbers? I know that people have had less significant SUBJECTIVE effects in 'feeling' well, however, has anyone found that with HCG... their numbers simply didn't budge?

I finally got my Thyroid improved and began HCG a month ago. Novarel 250 iu M/W/F/S to 1000iu/wk. My test/bio did NOTHING, maybe up a few points, but well within normal measurment variance.

E2 is stable as well.

REALLY NOTHING happened at all to speak of...

Maybe the novarel was no good?

Just out of curiosity - did you think you felt any better? Or during the process were you pretty cognizant that no changes were occurring?

[GirlyMan]

Has anyone ever tried HCG and seen no significant effect on numbers? ... My test/bio did NOTHING, maybe up a few points, but well within normal measurment variance. ... REALLY NOTHING happened at all to speak of...

Wouldn't that indicate that your fellas are already operating at peak output so they just effectively ignore any additional prompting from the HCG signal?

[Dadnatron]

Wouldn't that indicate that your fellas are already operating at peak output so they just effectively ignore any additional prompting from the HCG signal?

That would seem so, however, my Total Test was about twice what it is now in September, before I began Secretropin. But also before my thyroid went on the Fritz.

Perhaps it is just because my Thyroid was goofed up to begin with and it will take time to improve. But I would be willing to try HMG for a bit, to see if they will boost at all. I don't want to be expecting more out of them than they are capable of, but I also don't want to ignore them if they have the potential, and being 41... I would think they should be extremely 'boostable' on their own.

I have been taking DHEA 50 mg/d as well. To ensure that there is adequate precursor.

I don't want to STAY on HMG, but I would be willing to 'try it' to see if they respond.

I don't think the Novarel was a problem, it was out of my local pharmacy.


............


As far as feeling better, maybe I did... I wouldn't put it past placebo however. I felt like I was gaining muscle a bit faster, but really nothing that I would believe as a true change from before.

[seekonk]

Has anyone ever tried HCG and seen no significant effect on numbers? I know that people have had less significant SUBJECTIVE effects in 'feeling' well, however, has anyone found that with HCG... their numbers simply didn't budge?

I finally got my Thyroid improved and began HCG a month ago. Novarel 250 iu M/W/F/S to 1000iu/wk. My test/bio did NOTHING, maybe up a few points, but well within normal measurment variance.

E2 is stable as well.

REALLY NOTHING happened at all to speak of...

Isn't that a typical replacement dose?

A lot has probably happened: Your LH signal has been shut down and replaced by the HCG. But since you were probably not secondary, your LH signal has been replaced by only a roughly equivalent dose of HCG. So given that this is only a replacement dose, why would you expect anything to change?

Now if you had used a more-than-replacement dose, then I would say you should have expected a change. But you didn't.

[LowLH2011]

Isn't that a typical replacement dose?

A lot has probably happened: Your LH signal has been shut down and replaced by the HCG. But since you were probably not secondary, your LH signal has been replaced by only a roughly equivalent dose of HCG. So given that this is only a replacement dose, why would you expect anything to change?

Now if you had used a more-than-replacement dose, then I would say you should have expected a change. But you didn't.


Seekonk,
Can you elaborate on "replacement dose"? I have low LH and am trying to "replace" LH with HCG, to achieve a better quality of life. My Uro has prescribed 2000 (two thousand) IU of Novarel every 3 days. I am scouring thus forum to try to justify that big dose.

[jack1-979]

Seekonk,
Can you elaborate on "replacement dose"? I have low LH and am trying to "replace" LH with HCG, to achieve a better quality of life. My Uro has prescribed 2000 (two thousand) IU of Novarel every 3 days. I am scouring thus forum to try to justify that big dose.

Seekonks post is over 18 months old. His protocol has, in all likelihood, changed since that time.

I have, however, had success with 100 IU per day. It almost tripled my T levels. Search for my post on HCG. Any questions, feel free to ask.