5-HTP. Anyone like this crap?

[ok3671]

OK...so tried this last night. I keep reading about how great it is, so I thought I'd try it.

It's supposed to help with sleep and mood....yada yada.

I started with a 100mg dose.

Worst night of sleep I have had in a long time. I felt like I was half asleep, half awake all night, and vivid dreams, but it was like I knew I was dreaming, because I wasn't really sleeping. Weird. I've had the runs alll day too.

anyways...I feel like hell today, and wanted to vent. :)

Anyone else have a bad reaction to it?

[Dadoo]

OK...so tried this last night. I keep reading about how great it is, so I thought I'd try it.

It's supposed to help with sleep and mood....yada yada.

I started with a 100mg dose.

Worst night of sleep I have had in a long time. I felt like I was half asleep, half awake all night, and vivid dreams, but it was like I knew I was dreaming, because I wasn't really sleeping. Weird. I've had the runs alll day too.

anyways...I feel like hell today, and wanted to vent. :)

Anyone else have a bad reaction to it?
Try a much lower dose.

[Bulldog]

OK...so tried this last night. I keep reading about how great it is, so I thought I'd try it.

It's supposed to help with sleep and mood....yada yada.

I started with a 100mg dose.

Worst night of sleep I have had in a long time. I felt like I was half asleep, half awake all night, and vivid dreams, but it was like I knew I was dreaming, because I wasn't really sleeping. Weird. I've had the runs alll day too.

anyways...I feel like hell today, and wanted to vent. :)

Anyone else have a bad reaction to it?

100mg may be too much. I can't take any more than 50mg or I have similar problems. Try 50mg and see how it goes.

[Wise Guy]

100mg may be too much. I can't take any more than 50mg or I have similar problems. Try 50mg and see how it goes.

Same here. 50mg is plenty

And Brownb, lets be a little more gentlemanly w/ the thread titles.

[ok3671]

Same here. 50mg is plenty

And Brownb, lets be a little more gentlemanly w/ the thread titles.



Ok, I'll try lower....maybe.

and compared to what I really wanted to say, I am being gentlemanly. :)

I get your point though.

[cumkwakka]

i live on this stuff (deep sleep benefits)
50 mg is good, 100 is too much for me

depends on brand also

[ok3671]

i live on this stuff (deep sleep benefits)
50 mg is good, 100 is too much for me

depends on brand also

What brand are you using?

[dot1]

I have been taking in the morning to help with anxiety, running low on Ativan. It seems to mellow me out. I have taken it in the evenings for sleep, vivid dreams.

[Wise Guy]

What brand are you using?

I use biotest Z-12 - my favorite sleep supplement.

Sometimes I just run Now 50mg.

[chipdouglas]

Also, it's important to get a 5-HTP product from a reliable brand, to minimize Peak-X contamination, though it doesn't seem to be that much of a problem.

same here, 50 mg is pretty much the sweet spot for me. I tried more, and didn't get any adverse reaction, but just felt too drowsy.

[invictus]

Shouldn't one supplement with L-Dopa/L-Tyrosine along with the 5-HTP, assuming that Serotonin/Dopamine have an inverse relationship? Meaning, when one raises, the other falls? Or do they have minimal/no feedback on each other?

[simpllyhuge]

my sleep doc(i over sleep), said that seratonin slows down sleep phases and that one might just be sleeping deeper during the end of the night. I however have a lot more memorable dreams the whole night, so I don't know if I believe him.

[wondering]

what does it mean if 50mg makes you feel depressed. It was a one time experience but took it at bedtime once and woke in middle of night feeling so amazingly down. Maybe Ill try it again to see if it was unrelated but didnt feel like it.

[jasonshadow]

I take 200-400mg of 5-HTP. I also balance it out with L-Tyrosine and L-Cystine. Typically by taking just 5-HTP alone you can deplete your dopamine and vice versa.

[ok3671]

I take 200-400mg of 5-HTP. I also balance it out with L-Tyrosine and L-Cystine. Typically by taking just 5-HTP alone you can deplete your dopamine and vice versa.

well...it sure did something to me, and I know it's more than just a poor nights sleep. I have felt horrible all day. Very tired, and tense. An almost dull headache that I can't seem to shake.

I'll get a good nights sleep tonight...so hopefully tomorrow I feel normal!

[chipdouglas]

Have any of you 5HTP users noticed increased sex drive on 5HTP ? I did, and better/faster erections as well.

[cumkwakka]

What brand are you using?

i now use a local herbal shop brand which seems to be working
my g/f uses solgar and doesn't find it quite as effective as this brand even at higher dose

i used doctors best which was really good

also used youngagain brand also pretty good

[chilln]

OK...so tried this last night. I keep reading about how great it is, so I thought I'd try it.

It's supposed to help with sleep and mood....yada yada.

I started with a 100mg dose.


If 5-HTP is going to work for you at all, then 100mg is usually too high a dose.

5-HTP, when metabolised during sleep, can convert into either melatonin (good) or seratonin (bad).

In your case your dose resulted in too much conversion into seratonin.

I find that 50 mg works OK for me, but 100mg results in the same issues as you noted above.

.

[Bob45]

If it is supposed to help with mood I better try some.

[jasonshadow]

[QUOTE=chilln;75794]If 5-HTP is going to work for you at all, then 100mg is usually too high a dose.

With neruotransmitters being so drasticly different from one person to the next I don't know how one can make a statement that 100mg is too high of dosage. 5-htp like most things can be dose dependent. 50mg did aboslutely nothing for me. I did not feel the effects from 5-htp until I got to 200 mg.

[ok3671]

[QUOTE=chilln;75794]If 5-HTP is going to work for you at all, then 100mg is usually too high a dose.

With neruotransmitters being so drasticly different from one person to the next I don't know how one can make a statement that 100mg is too high of dosage. 5-htp like most things can be dose dependent. 50mg did aboslutely nothing for me. I did not feel the effects from 5-htp until I got to 200 mg.

I believe he was commenting particually to me, since I posted the thread and asked the question. It's very obvious for me...that 100MG is way to much. I still feel like hell, and again last night..didn't sleep well. While, I do feel better than yesterday, I am still feeling the affects of 1 100mg dose, over 36 hours ago.

Maybe, after I get back to feelingn normal, I'll try a 50mg dose...on a weekend.

[jasonshadow]

[QUOTE=jasonshadow;75802]

I believe he was commenting particually to me, since I posted the thread and asked the question. It's very obvious for me...that 100MG is way to much. I still feel like hell, and again last night..didn't sleep well. While, I do feel better than yesterday, I am still feeling the affects of 1 100mg dose, over 36 hours ago.

Maybe, after I get back to feelingn normal, I'll try a 50mg dose...on a weekend.

Yes...you are correct. I misinterpreted chilln's statement. In your case it does seem 100mg is too much. There are some who report good effects from even 25mg. If one has high levels of Serotonin naturally and then takes something like 5-HTP it can cause a rare condition called Serotnin Syndrome.

Serotonin syndrome symptoms typically occur within several hours of taking a new drug or increasing the dose of a drug you're already taking. Signs and symptoms include:

Agitation or restlessness
Confusion
Rapid heart rate
Dilated pupils
Loss of muscle coordination or twitching muscles
Heavy sweating
Diarrhea
Headache
Shivering
Goose bumps
Severe serotonin syndrome can be life-threatening. Signs and symptoms include:

High fever
Seizures
Irregular heartbeat
Unconsciousness

[ok3671]

well..maybe that's me.


[QUOTE=brownb01;75804]


Agitation or restlessness CHECK
Confusion CHECK
Rapid heart rate
Dilated pupils
Loss of muscle coordination or twitching muscles
Heavy sweating CHECK
Diarrhea CHECK
Headache CHECK
Shivering
Goose bumps


Severe serotonin syndrome can be life-threatening. Signs and symptoms include:

High fever
Seizures
Irregular heartbeat
Unconsciousness

[chipdouglas]

Shouldn't one supplement with L-Dopa/L-Tyrosine along with the 5-HTP, assuming that Serotonin/Dopamine have an inverse relationship? Meaning, when one raises, the other falls? Or do they have minimal/no feedback on each other?

Serotonin and Dopamine are tied at the hips like Dr. Romeo Mariano often wrote, when you raise serotonin enough, dopamine will drop as a result, and vice versa.

[chipdouglas]

[QUOTE=brownb01;75804]

Yes...you are correct. I misinterpreted chilln's statement. In your case it does seem 100mg is too much. There are some who report good effects from even 25mg. If one has high levels of Serotonin naturally and then takes something like 5-HTP it can cause a rare condition called Serotnin Syndrome.

Serotonin syndrome symptoms typically occur within several hours of taking a new drug or increasing the dose of a drug you're already taking. Signs and symptoms include:

Agitation or restlessness
Confusion
Rapid heart rate
Dilated pupils
Loss of muscle coordination or twitching muscles
Heavy sweating
Diarrhea
Headache
Shivering
Goose bumps
Severe serotonin syndrome can be life-threatening. Signs and symptoms include:

High fever
Seizures
Irregular heartbeat
Unconsciousness

Serotonin syndrome isn't a very common clinical manifestation. I listened to teleconference from Sanesco and that's what the docs giving the lecture said.

[invictus]

With neruotransmitters being so drasticly different from one person to the next I don't know how one can make a statement that 100mg is too high of dosage. 5-htp like most things can be dose dependent. 50mg did aboslutely nothing for me. I did not feel the effects from 5-htp until I got to 200 mg.[/QUOTE]

I wholeheartedly agree; 100 mg is too much for me to take at one time.

[invictus]

With neruotransmitters being so drasticly different from one person to the next I don't know how one can make a statement that 100mg is too high of dosage. 5-htp like most things can be dose dependent. 50mg did aboslutely nothing for me. I did not feel the effects from 5-htp until I got to 200 mg.

I wholeheartedly agree; 100 mg is too much for me to take at one time.

[milnerb1]

This is a fascinating discussion and very helpful.

I take 3 mg time release melatonin at bedtime with good effects.

I used to take 100 mg of 5-HTP in the morning because I was told to take it on an empty stomach.

However, a few weeks ago, I started taking the 5-HTP at night with my melatonin.

I never made the connection until now, but it appears that my recent issue with restless sleep could be explained by taking 100 mg 5-HTP before bed.

I will switch my doeses back to morning and see if my sleep improves.

Thanks for the helpful discussion.