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04-10-2008, 03:40 PM
http://www.ncbi.nlm.nih.gov/entrez/query/egifs/http:--highwire.stanford.edu-icons-externalservices-pubmed-custom-bioscientifica_full.gif (http://eje-online.org/cgi/pmidlookup?view=long&pmid=18299474) Related Articles (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Display&dopt=PubMed_PubMed&from_uid=18299474) Hypoactive sexual desire in transsexual women: prevalence and association with testosterone levels.
Eur J Endocrinol. 2008 Mar;158(3):393-9
Authors: Elaut E, De Cuypere G, De Sutter P, Gijs L, Van Trotsenburg M, Heylens G, Kaufman JM, Rubens R, T'sjoen G
OBJECTIVE: An unknown proportion of transsexual women (defined as post-operative male-to-female transsexuals on oestrogen replacement) experience hypoactive sexual desire disorder (HSDD). It has been suggested that the absence of ovarian androgen production together with oestrogen treatment-related increase in sex hormone-binding globulin (SHBG) levels could be leading to HSDD, due to low levels of biologically available testosterone. This study wishes to document the HSDD prevalence among transsexual women and the possible association to androgen levels. DESIGN: Cross-sectional study. METHODS: Transsexual women (n=62) and a control group of ovulating women (n=30) participated in this study. Questionnaires measuring sexual desire (sexual desire inventory) and relationship and sexual satisfaction (Maudsley Marital Questionnaire) were completed. Serum levels of total testosterone, LH and SHBG were measured in blood samples obtained at random in transsexual women and in the early follicular phase in ovulating women. RESULTS: The transsexual group had lower levels of total and calculated free testosterone (both P
Eur J Endocrinol. 2008 Mar;158(3):393-9
Authors: Elaut E, De Cuypere G, De Sutter P, Gijs L, Van Trotsenburg M, Heylens G, Kaufman JM, Rubens R, T'sjoen G
OBJECTIVE: An unknown proportion of transsexual women (defined as post-operative male-to-female transsexuals on oestrogen replacement) experience hypoactive sexual desire disorder (HSDD). It has been suggested that the absence of ovarian androgen production together with oestrogen treatment-related increase in sex hormone-binding globulin (SHBG) levels could be leading to HSDD, due to low levels of biologically available testosterone. This study wishes to document the HSDD prevalence among transsexual women and the possible association to androgen levels. DESIGN: Cross-sectional study. METHODS: Transsexual women (n=62) and a control group of ovulating women (n=30) participated in this study. Questionnaires measuring sexual desire (sexual desire inventory) and relationship and sexual satisfaction (Maudsley Marital Questionnaire) were completed. Serum levels of total testosterone, LH and SHBG were measured in blood samples obtained at random in transsexual women and in the early follicular phase in ovulating women. RESULTS: The transsexual group had lower levels of total and calculated free testosterone (both P